An interactive visualization tool for multi-channel confocal microscopy data in neurobiology research.

ABSTRACT: Confocal microscopy is widely used in neurobiology for studying the three-dimensional structure of the nervous system. Confocal image data are often multi-channel, with each channel resulting from a different fluorescent dye or fluorescent protein; one channel may have dense data, while another has sparse; and there are often structures at several spatial scales: subneuronal domains, neurons, and large groups of neurons (brain regions). Even qualitative analysis can therefore require visualization using techniques and parameters fine-tuned to a particular dataset. Despite the plethora of volume rendering techniques that have been available for many years, the techniques standardly used in neurobiological research are somewhat rudimentary, such as looking at image slices or maximal intensit

SUBMITTER: Wan Y 

PROVIDER: S-EPMC2874972 | biostudies-literature | 2009 Nov-Dec

REPOSITORIES: biostudies-literature