Complex fractionated atrial electrograms: properties of time-domain versus frequency-domain methods.

ABSTRACT:

Background

Complex fractionated atrial electrograms (CFAEs) are thought to identify high-frequency electrical sources and have become an important target for radiofrequency ablation of atrial fibrillation (AF). Methods used to identify CFAEs and locate suitable ablation sites usually depend on subjective analysis of the electrograms but may also involve objective, computer-based paradigms through either time- or frequency-domain approaches.

Methods

We generated a set of simulated test electrograms, which were defined by a combination of a basic cycle length, phase-resetting noise, and phase-preserving noise, accounting for far-field effects. The simulated electrograms were analyzed separately by well-known basic time-domain (complex fractionated electrogram [CFE]) and freque

SUBMITTER: Grzeda KR 

PROVIDER: S-EPMC2875118 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature