Safety of tPA in stroke mimics and neuroimaging-negative cerebral ischemia.

ABSTRACT:

Background

Patients with acute neurologic symptoms may have other causes simulating ischemic stroke, called stroke mimics (SM), but they may also have averted strokes that do not appear as infarcts on neuroimaging, which we call neuroimaging-negative cerebral ischemia (NNCI). We determined the safety and outcome of IV thrombolysis within 3 hours of symptom onset in patients with SM and NNCI.

Methods

Patients treated with IV tissue plasminogen activator (tPA) within 3 hours of symptom onset were identified from our stroke registry from June 2004 to October 2008. We collected admission NIH Stroke Scale (NIHSS) score, modified Rankin score (mRS), length of stay (LOS), symptomatic intracerebral hemorrhage (sICH), and discharge diagnosis.

Results

Among 512 treated patients

SUBMITTER: Chernyshev OY 

PROVIDER: S-EPMC2875935 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature