Steroid receptor expression in the fish inner ear varies with sex, social status, and reproductive state.

ABSTRACT:

Background

Gonadal and stress-related steroid hormones are known to influence auditory function across vertebrates but the cellular and molecular mechanisms responsible for steroid-mediated auditory plasticity at the level of the inner ear remain unknown. The presence of steroid receptors in the ear suggests a direct pathway for hormones to act on the peripheral auditory system, but little is known about which receptors are expressed in the ear or whether their expression levels change with internal physiological state or external social cues. We used qRT-PCR to measure mRNA expression levels of multiple steroid receptor subtypes (estrogen receptors: ERalpha, ERbetaa, ERbetab; androgen receptors: ARalpha, ARbeta; corticosteroid receptors: GR2, GR1a/b, MR) and aromatase in the main

SUBMITTER: Maruska KP 

PROVIDER: S-EPMC2876163 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature