Structure and protein-protein interaction studies on Chlamydia trachomatis protein CT670 (YscO Homolog).

ABSTRACT: Comparative genomic studies have identified many proteins that are found only in various Chlamydiae species and exhibit no significant sequence similarity to any protein in organisms that do not belong to this group. The CT670 protein of Chlamydia trachomatis is one of the proteins whose genes are in one of the type III secretion gene clusters but whose cellular functions are not known. CT670 shares several characteristics with the YscO protein of Yersinia pestis, including the neighboring genes, size, charge, and secondary structure, but the structures and/or functions of these proteins remain to be determined. Although a BLAST search with CT670 did not identify YscO as a related protein, our analysis indicated that these two proteins exhibit significant sequence similarity. In this paper

SUBMITTER: Lorenzini E 

PROVIDER: S-EPMC2876502 | biostudies-literature | 2010 Jun

REPOSITORIES: biostudies-literature