Ontology highlight
ABSTRACT:
SUBMITTER: Udler MS
PROVIDER: S-EPMC2876886 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Human molecular genetics 20100323 12
Recent genome-wide association studies have identified a breast cancer susceptibility locus on 16q12 with an unknown biological basis. We used a set of single nucleotide polymorphism (SNP) markers to generate a fine-scale map and narrowed the region of association to a 133 kb DNA segment containing the largely uncharacterized hypothetical gene LOC643714, a short intergenic region and the 5' end of TOX3. Re-sequencing this segment in European subjects identified 293 common polymorphisms, includin ...[more]