Diagnosis and phylogenetic analysis of Orf virus from goats in China: a case report.

ABSTRACT:

Background

Orf virus (ORFV) is the etiological agent of contagious pustular dermatitis and is the prototype of the genus Parapoxvirus (PPV). It causes a severe exanthematous dermatitis that afflicts domestic and wild small ruminants.

Case presentation

In the present study, an outbreak of proliferative dermatitis in farmed goats. The presence of ORFV in tissue scrapings from the lips was confirmed by B2L gene polymerase chain reaction (PCR) amplification. The molecular characterization of the ORFV was performed using PCR amplification, DNA sequencing and phylogenetic analysis of the B2L gene.

Conclusion

The results of this investigation indicated that the outbreak was caused by infection with an ORFV that was closely related genetically to Nantou (DQ934351), which was

SUBMITTER: Zhang K 

PROVIDER: S-EPMC2877020 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature