Synthesis of a monophosphoryl lipid A derivative and its conjugation to a modified form of a tumor-associated carbohydrate antigen GM3.

ABSTRACT: An efficient synthesis of a derivative of monophosphoryl lipid A suitable for coupling to various structures for the construction of glycoconjugate vaccines and its conjugation with an N-modified form of the tumor-associated antigen GM3 is presented.

SUBMITTER: Wang Q 

PROVIDER: S-EPMC2877631 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature