High prevalence and genetic diversity of HCV among HIV-1 infected people from various high-risk groups in China.

ABSTRACT:

Background

Co-infection with HIV-1 and HCV is a significant global public health problem and a major consideration for anti-HIV-1 treatment. HCV infection among HIV-1 positive people who are eligible for the newly launched nationwide anti-HIV-1 treatment program in China has not been well characterized.

Methodology

A nationwide survey of HIV-1 positive injection drug uses (IDU), former paid blood donors (FBD), and sexually transmitted cases from multiple provinces including the four most affected provinces in China was conducted. HCV prevalence and genetic diversity were determined. We found that IDU and FBD have extremely high rates of HCV infection (97% and 93%, respectively). Surprisingly, people who acquired HIV-1 through sexual contact also had a higher rate of HCV infe

SUBMITTER: Shang H 

PROVIDER: S-EPMC2877711 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature