Virus detection and monitoring of viral load in Crimean-Congo hemorrhagic fever virus patients.

ABSTRACT: We developed a real-time reverse transcription--PCR that detected 1,164 copies/mL of Crimean-Congo hemorrhagic fever virus per milliliter of serum at 95% probability (probit analysis) and was 100% concordant with nested PCR on 63 samples from 31 patients with confirmed infection. Infected patients who died appeared to have higher viral loads; low viral loads correlated with IgG detection.

SUBMITTER: Wolfel R 

PROVIDER: S-EPMC2878241 | biostudies-literature | 2007 Jul

REPOSITORIES: biostudies-literature