Category-specific versus category-general semantic impairment induced by transcranial magnetic stimulation.

ABSTRACT: Semantic cognition permits us to bring meaning to our verbal and nonverbal experiences and to generate context- and time-appropriate behavior. It is core to language and nonverbal skilled behaviors and, when impaired after brain damage, it generates significant disability. A fundamental neuroscience question is, therefore, how does the brain code and generate semantic cognition? Historical and some contemporary theories emphasize that conceptualization stems from the joint action of modality-specific association cortices (the "distributed" theory) reflecting our accumulated verbal, motor, and sensory experiences. Parallel studies of semantic dementia, rTMS in normal participants, and neuroimaging indicate that the anterior temporal lobe (ATL) plays a crucial and necessary role in conceptua

SUBMITTER: Pobric G 

PROVIDER: S-EPMC2878637 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature