Effects of childhood body size on breast cancer tumour characteristics.

ABSTRACT:

Introduction

Although a role of childhood body size in postmenopausal breast cancer risk has been established, less is known about its influence on tumour characteristics.

Methods

We studied the relationships between childhood body size and tumour characteristics in a Swedish population-based case-control study consisting of 2,818 breast cancer cases and 3,111 controls. Our classification of childhood body size was derived from a nine-level somatotype. Relative risks were estimated by odds ratios with 95% confidence intervals, derived from fitting unconditional logistic regression models. Association between somatotype at age 7 and tumour characteristics were evaluated in a case-only analysis where P values for heterogeneity were obtained by performing one degree of freedom

SUBMITTER: Li J 

PROVIDER: S-EPMC2879571 | biostudies-literature | 2010

REPOSITORIES: biostudies-literature