Analysis of gene evolution and metabolic pathways using the Candida Gene Order Browser.

ABSTRACT:

Background

Candida species are the most common cause of opportunistic fungal infection worldwide. Recent sequencing efforts have provided a wealth of Candida genomic data. We have developed the Candida Gene Order Browser (CGOB), an online tool that aids comparative syntenic analyses of Candida species. CGOB incorporates all available Candida clade genome sequences including two Candida albicans isolates (SC5314 and WO-1) and 8 closely related species (Candida dubliniensis, Candida tropicalis, Candida parapsilosis, Lodderomyces elongisporus, Debaryomyces hansenii, Pichia stipitis, Candida guilliermondii and Candida lusitaniae). Saccharomyces cerevisiae is also included as a reference genome.

Results

CGOB assignments of homology were manually curated based on sequence similari

SUBMITTER: Fitzpatrick DA 

PROVIDER: S-EPMC2880306 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature