Ontology highlight
ABSTRACT:
SUBMITTER: Moore SM
PROVIDER: S-EPMC2885287 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
Moore Shelley M SM Liang Tiebing T Graves Tamara J TJ McCall Kevin M KM Carr Lucinda G LG Ehlers Cindy L CL
Human genomics 20090701 4
This paper reports the identification of a novel cytosolic aldehyde dehydrogenase 1 ( ALDH1A1 ) allele. One hundred and sixty-two Indo-Trinidadian and 85 Afro-Trinidadian individuals were genotyped. A novel ALDH1A1 allele, ALDH1A1*4 , was identified in an Indo-Trinidadian alcoholic with an A inserted at position -554 relative to the translational start site, +1. It was concluded that a wider cross-section of individuals needs to be evaluated in order to determine the representative frequency of ...[more]