NeuroML: a language for describing data driven models of neurons and networks with a high degree of biological detail.

ABSTRACT: Biologically detailed single neuron and network models are important for understanding how ion channels, synapses and anatomical connectivity underlie the complex electrical behavior of the brain. While neuronal simulators such as NEURON, GENESIS, MOOSE, NEST, and PSICS facilitate the development of these data-driven neuronal models, the specialized languages they employ are generally not interoperable, limiting model accessibility and preventing reuse of model components and cross-simulator validation. To overcome these problems we have used an Open Source software approach to develop NeuroML, a neuronal model description language based on XML (Extensible Markup Language). This enables these detailed models and their components to be defined in a standalone form, allowing them to be used

SUBMITTER: Gleeson P 

PROVIDER: S-EPMC2887454 | biostudies-literature | 2010 Jun

REPOSITORIES: biostudies-literature