Neural correlates of sequence encoding in visuomotor learning.

ABSTRACT: To examine the neural basis of sequence learning, a fundamental but poorly understood human ability, we recorded event-related potentials (ERPs) while subjects viewed and memorized randomly directed sequences of motions for later imitation. Previously, we found that the amplitude of ERPs elicited by successive motion segments decreased as a function of each segment's serial position. This happened when subjects were required to remember the sequence, but not when they were performing a perceptual task. Here, to study the functional significance of this amplitude gradient in sequence learning, we presented each sequence several times in succession and examined changes in ERP amplitude as subjects learned the sequence through repeated observation and imitation. Behaviorally, with each repeti

SUBMITTER: Agam Y 

PROVIDER: S-EPMC2887627 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature