Depressive symptoms and clinical status during the Treatment of Adolescent Suicide Attempters (TASA) Study.

ABSTRACT:

Objective

To examine the course of depression during the treatment of adolescents with depression who had recently attempted suicide.

Method

Adolescents (N = 124), ages 12 to 18 years, with a 90-day history of suicide attempt, a current diagnosis of depressive disorder (96.0% had major depressive disorder), and a Children's Depression Rating Scale-Revised (CDRS-R) score of 36 or higher, entered a 6-month treatment with antidepressant medication, cognitive-behavioral therapy focused on suicide prevention, or their combination (Comb), at five academic sites. Treatment assignment could be either random or chosen by study participants. Intent-to-treat, mixed effects regression models of depression and other relevant ratings were estimated. Improvement and remission rates were co

SUBMITTER: Vitiello B 

PROVIDER: S-EPMC2889199 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature