Association of testosterone and sex hormone-binding globulin with metabolic syndrome and insulin resistance in men.

ABSTRACT:

Objective

We sought to assess the associations of testosterones and sex hormone-binding globulin (SHBG) with metabolic syndrome and insulin resistance in men.

Research design and methods

We defined metabolic syndrome according to the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Among men aged >or=20 years who participated in the Third National Health and Nutrition Examination Survey (n = 1,226), the Cox proportional hazards model was used to estimate the prevalence ratio and 95% CI of metabolic syndrome according to circulating concentrations of testosterones and SHBG.

Results

After adjustment for age, race/ethnicity, smoking status, alcohol intake, physical activity level, LDL cholest

SUBMITTER: Li C 

PROVIDER: S-EPMC2890370 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature