Understanding the evolutionary relationships and major traits of Bacillus through comparative genomics.

ABSTRACT:

Background

The presence of Bacillus in very diverse environments reflects the versatile metabolic capabilities of a widely distributed genus. Traditional phylogenetic analysis based on limited gene sampling is not adequate for resolving the genus evolutionary relationships. By distinguishing between core and pan-genome, we determined the evolutionary and functional relationships of known Bacillus.

Results

Our analysis is based upon twenty complete and draft Bacillus genomes, including a newly sequenced Bacillus isolate from an aquatic environment that we report for the first time here. Using a core genome, we were able to determine the phylogeny of known Bacilli, including aquatic strains whose position in the phylogenetic tree could not be unambiguously determined in the pa

SUBMITTER: Alcaraz LD 

PROVIDER: S-EPMC2890564 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature