Comparative genomics of the family Vibrionaceae reveals the wide distribution of genes encoding virulence-associated proteins.

ABSTRACT:

Background

Species of the family Vibrionaceae are ubiquitous in marine environments. Several of these species are important pathogens of humans and marine species. Evidence indicates that genetic exchange plays an important role in the emergence of new pathogenic strains within this family. Data from the sequenced genomes of strains in this family could show how the genes encoded by all these strains, known as the pangenome, are distributed. Information about the core, accessory and panproteome of this family can show how, for example, genes encoding virulence-associated proteins are distributed and help us understand how virulence emerges.

Results

We deduced the complete set of orthologs for eleven strains from this family. The core proteome consists of 1,882 orthologous gr

SUBMITTER: Lilburn TG 

PROVIDER: S-EPMC2890568 | biostudies-literature | 2010 Jun

REPOSITORIES: biostudies-literature