Comparative effectiveness of 5 smoking cessation pharmacotherapies in primary care clinics.

ABSTRACT:

Background

Randomized efficacy clinical trials conducted in research settings may not accurately reflect the benefits of tobacco dependence treatments when used in real-world clinical settings. Effectiveness trials (eg, in primary care settings) are needed to estimate the benefits of cessation treatments in real-world use.

Methods

A total of 1346 primary care patients attending routine appointments were recruited by medical assistants in 12 primary care clinics. Patients were randomly assigned to 5 active pharmacotherapies: 3 monotherapies (nicotine patch, nicotine lozenge, and bupropion hydrochloride sustained release [SR]) and 2 combination therapies (patch + lozenge and bupropion SR + lozenge). Patients were referred to a telephone quit line for cessation counseling. Prim

SUBMITTER: Smith SS 

PROVIDER: S-EPMC2891174 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature