Occupational exposure to organic solvents and breast cancer in women.

ABSTRACT:

Background

Although studies in rodents suggest possible associations between exposure to organic solvents and breast cancer, the evidence in humans is limited.

Methods

We evaluated job histories of 2383 incident breast cancer cases diagnosed during 2000-2003, and 2502 controls who participated in a large population-based case-control study in Poland. Industrial hygienists reviewed occupational histories and developed exposure metrics for total organic solvents and benzene. Unconditional logistic regression analyses estimated ORs and 95% CIs as the measure of association with breast cancer, controlling for breast cancer risk factors. Stratified analyses examined the potential modification by known breast cancer risk factors. Associations were also evaluated by oestrogen and p

SUBMITTER: Peplonska B 

PROVIDER: S-EPMC2891315 | biostudies-literature | 2010 Nov

REPOSITORIES: biostudies-literature