Genetics of food allergy.

ABSTRACT:

Purpose of review

Food allergy, a growing clinical and public health problem in the United States and worldwide, is likely determined by multiple environmental and genetic factors. The purpose of this review is to summarize recent advances in food allergy genetic research.

Recent findings

There is compelling evidence that genetic factors may play a role in food allergy. However, the specific genetic loci that may modulate individual risk of food allergy remain to be identified. To date, only a limited number of candidate gene association studies of food allergy have been reported. Polymorphism(s) in nine genes have been associated with the incidence of food allergy or food allergy severity in at least one study. But most of these findings remain to be replicated in independe

SUBMITTER: Hong X 

PROVIDER: S-EPMC2892276 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature