Dairy intake and 1,25-dihydroxyvitamin D levels in men at high risk for prostate cancer.

ABSTRACT:

Objective

Dairy food intake has been associated with prostate cancer in previous work, but the mechanism by which this occurs is unknown. Dairy calcium may suppress circulating levels of potentially cancer-protective 1,25-hydroxyvitamin D (1,25(OH)2D). We examined the associations of dairy, milk, calcium, and vitamin D intake with plasma 1,25(OH)2D levels among 296 men (194 black, 102 non-black) enrolled in a high risk program for prostate cancer from 10/96 to 10/07.

Methods

All participants completed diet and health history questionnaires and provided plasma samples, which were assessed for levels of 25-hydroxyvitamin D and 1,25(OH)2D. We used multivariate linear regression to examine associations with 1,25(OH)2D.

Results

After adjustment for age, race, energy intake

SUBMITTER: Tseng M 

PROVIDER: S-EPMC2895954 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature