NMR Constraints Analyser: a web-server for the graphical analysis of NMR experimental constraints.

ABSTRACT: Nuclear magnetic resonance (NMR) spectroscopy together with X-ray crystallography, are the main techniques used for the determination of high-resolution 3D structures of biological molecules. The output of an NMR experiment includes a set of lower and upper limits for the distances (constraints) between pairs of atoms. If the number of constraints is high enough, there will be a finite number of possible conformations (models) of the macromolecule satisfying the data. Thus, the more constraints are measured, the better defined these structures will be. The availability of a user-friendly tool able to help in the analysis and interpretation of the number of experimental constraints per residue, is thus of valuable importance when assessing the levels of structure definition of NMR solved bi

SUBMITTER: Heller DM 

PROVIDER: S-EPMC2896076 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature