PiRaNhA: a server for the computational prediction of RNA-binding residues in protein sequences.

ABSTRACT: The PiRaNhA web server is a publicly available online resource that automatically predicts the location of RNA-binding residues (RBRs) in protein sequences. The goal of functional annotation of sequences in the field of RNA binding is to provide predictions of high accuracy that require only small numbers of targeted mutations for verification. The PiRaNhA server uses a support vector machine (SVM), with position-specific scoring matrices, residue interface propensity, predicted residue accessibility and residue hydrophobicity as features. The server allows the submission of up to 10 protein sequences, and the predictions for each sequence are provided on a web page and via email. The prediction results are provided in sequence format with predicted RBRs highlighted, in text format with th

SUBMITTER: Murakami Y 

PROVIDER: S-EPMC2896099 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature