Entrained rhythmic activities of neuronal ensembles as perceptual memory of time interval.

ABSTRACT: The ability to process temporal information is fundamental to sensory perception, cognitive processing and motor behaviour of all living organisms, from amoebae to humans. Neural circuit mechanisms based on neuronal and synaptic properties have been shown to process temporal information over the range of tens of microseconds to hundreds of milliseconds. How neural circuits process temporal information in the range of seconds to minutes is much less understood. Studies of working memory in monkeys and rats have shown that neurons in the prefrontal cortex, the parietal cortex and the thalamus exhibit ramping activities that linearly correlate with the lapse of time until the end of a specific time interval of several seconds that the animal is trained to memorize. Many organisms can also mem

SUBMITTER: Sumbre G 

PROVIDER: S-EPMC2896960 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature