Feline lectin activity is critical for the cellular entry of feline infectious peritonitis virus.

ABSTRACT: Feline infectious peritonitis is a lethal disease of felids caused by systemic infection with a feline coronavirus. Here, we report identification and analysis of the feline homologue to the human lectin DC-SIGN and show that it is a coreceptor for virulent strains of serotype 1 and serotype 2 feline coronaviruses.

SUBMITTER: Regan AD 

PROVIDER: S-EPMC2897608 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature