Sequence and phylogenetic analysis of H7N3 avian influenza viruses isolated from poultry in Pakistan 1995-2004.

ABSTRACT:

Background

Avian influenza virus (AIV) infections have caused heavy economic losses to the poultry industry in Pakistan as well as numerous other regions worldwide. The first introduction of H7N3 AIV to Pakistan occurred during 1995, since then H7N3, H9N2 and H5N1 AIVs have each been sporadically isolated. This report evaluates the genetic origin of the H7N3 viruses from Pakistan collected 1995-2004 and how they disseminated within the country. To accomplish this we produced whole genome sequences for 6 H7N3 viruses and data for the HA and NA genes of an additional 7 isolates. All available sequence from H7N3 AIV from Pakistan was included in the analysis.

Results

Phylogenetic analysis revealed that there were two introductions of H7 into Pakistan and one N3 introduction. On

SUBMITTER: Abbas MA 

PROVIDER: S-EPMC2901269 | biostudies-literature | 2010 Jun

REPOSITORIES: biostudies-literature