Intake of cruciferous vegetables modifies bladder cancer survival.

ABSTRACT:

Background

Intake of cruciferous vegetables, a rich source of dietary isothiocyanates, has been inversely associated with risk of bladder cancer. Due to the potent antiproliferative effects of dietary isothiocyanates on bladder cancer in in vitro and in vivo models, cruciferous vegetable intake may also play a role in survival among patients with bladder cancer.

Methods

Using information obtained from the Roswell Park Cancer Institute Tumor Registry, patient medical records, and routinely collected questionnaire data, we examined potential associations between intake of cruciferous vegetables and survival among bladder cancer patients. As cooking can substantially reduce or destroy isothiocyanates, consumption of raw versus cooked cruciferous vegetables was examined separate

SUBMITTER: Tang L 

PROVIDER: S-EPMC2901397 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature