Arabidopsis extra large G-protein 2 (XLG2) interacts with the Gbeta subunit of heterotrimeric G protein and functions in disease resistance.

ABSTRACT: Heterotrimeric GTP-binding proteins, which consist of Galpha, Gbeta, and Ggamma subunits, play important roles in transducing extracellular signals perceived by cell surface receptors into intracellular physiological responses. In addition to a single prototypical Galpha protein (GPA1), Arabidopsis has three unique Galpha-like proteins, known as XLG1, XLG2, and XLG3, that have been found to be localized in nuclei, although their functions and mode of action remain largely unknown. Through a transcriptomic analysis, we found that XLG2 and XLG3 were rapidly induced by infection with the bacterial pathogen Pseudomonas syringae, whereas the XLG1 transcript level was not affected by pathogen infection. A reverse genetic screen revealed that the xlg2 loss-of-function mutation causes enhanced sus

SUBMITTER: Zhu H 

PROVIDER: S-EPMC2902900 | biostudies-literature | 2009 May

REPOSITORIES: biostudies-literature