Cytokines associated with bronchopulmonary dysplasia or death in extremely low birth weight infants.

ABSTRACT:

Objective

The goal was to develop multivariate logistic regression models for the outcome of bronchopulmonary dysplasia and/or death at postmenstrual age of 36 weeks by using clinical and cytokine data from the first 28 days.

Methods

For 1067 extremely low birth weight infants in the Neonatal Research Network of the National Institute of Child Health and Human Development, levels of 25 cytokines were measured in blood collected within 4 hours after birth and on days 3, 7, 14, and 21. Stepwise regression analyses using peak levels of the 25 cytokines and 15 clinical variables identified variables associated with bronchopulmonary dysplasia/death. Multivariate logistic regression analysis was performed for bronchopulmonary dysplasia/death by using variables selected through ste

SUBMITTER: Ambalavanan N 

PROVIDER: S-EPMC2903210 | biostudies-literature | 2009 Apr

REPOSITORIES: biostudies-literature