Analysis of the vp2 gene sequence of a new mutated mink enteritis parvovirus strain in PR China.

ABSTRACT:

Background

Mink enteritis virus (MEV) causes a highly contagious viral disease of mink with a worldwide distribution. MEV has a linear, single-stranded, negative-sense DNA with a genome length of approximately 5,000 bp. The VP2 protein is the major structural protein of the parvovirus encoded by the vp2 gene. VP2 is highly antigenic and plays important roles in determining viral host ranges and tissue tropisms. This study describes the bionomics and vp2 gene analysis of a mutated strain, MEV-DL, which was isolated recently in China and outlines its homologous relationships with other selected strains registered in Genbank.

Results

The MEV-DL strain can infect F81 cells with cytopathic effects. Pig erythrocytes were agglutinated by the MEV-DL strain. The generation of MEV-DL

SUBMITTER: Zuo J 

PROVIDER: S-EPMC2903559 | biostudies-literature | 2010 Jun

REPOSITORIES: biostudies-literature