Ontology highlight
ABSTRACT: Background
Experimental descriptions are typically stored as free text without using standardized terminology, creating challenges in comparison, reproduction and analysis. These difficulties impose limitations on data exchange and information retrieval.Results
The Ontology for Biomedical Investigations (OBI), developed as a global, cross-community effort, provides a resource that represents biomedical investigations in an explicit and integrative framework. Here we detail three real-world applications of OBI, provide detailed modeling information and explain how to use OBI.Conclusion
We demonstrate how OBI can be applied to different biomedical investigations to both facilitate interpretation of the experimental process and increase the computational processing and integration within the Semantic Web. The logical definitions of the entities involved allow computers to unambiguously understand and integrate different biological experimental processes and their relevant components.Availability
OBI is available at http://purl.obolibrary.org/obo/obi/2009-11-02/obi.owl.
SUBMITTER: Brinkman RR
PROVIDER: S-EPMC2903726 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Brinkman Ryan R RR Courtot Mélanie M Derom Dirk D Fostel Jennifer M JM He Yongqun Y Lord Phillip P Malone James J Parkinson Helen H Peters Bjoern B Rocca-Serra Philippe P Ruttenberg Alan A Sansone Susanna-Assunta SA Soldatova Larisa N LN Stoeckert Christian J CJ Turner Jessica A JA Zheng Jie J
Journal of biomedical semantics 20100622
<h4>Background</h4>Experimental descriptions are typically stored as free text without using standardized terminology, creating challenges in comparison, reproduction and analysis. These difficulties impose limitations on data exchange and information retrieval.<h4>Results</h4>The Ontology for Biomedical Investigations (OBI), developed as a global, cross-community effort, provides a resource that represents biomedical investigations in an explicit and integrative framework. Here we detail three ...[more]