The association of diabetes with colorectal cancer risk: the Multiethnic Cohort.

ABSTRACT:

Background

Diabetics have been found to have a greater risk of colorectal cancer than non-diabetics.

Methods

We examined whether this relationship differed by ethnic group, cancer site or tumour stage in a population-based prospective cohort, including 3549 incident colorectal cancer cases identified over a 13-year period (1993-2006) among 199 143 European American, African American, Native Hawaiian, Japanese American and Latino men and women in the Multiethnic Cohort.

Results

Diabetics overall had a significantly greater risk of colorectal cancer than did non-diabetics (relative risk (RR)=1.19, 95% confidence interval (CI)=1.09-1.29, P-value (P)<0.001). Positive associations were observed for colon cancer, cancers of both the right and left colon, and cancers diagnos

SUBMITTER: He J 

PROVIDER: S-EPMC2905298 | biostudies-literature | 2010 Jun

REPOSITORIES: biostudies-literature