A computational genomics pipeline for prokaryotic sequencing projects.

ABSTRACT:

Motivation

New sequencing technologies have accelerated research on prokaryotic genomes and have made genome sequencing operations outside major genome sequencing centers routine. However, no off-the-shelf solution exists for the combined assembly, gene prediction, genome annotation and data presentation necessary to interpret sequencing data. The resulting requirement to invest significant resources into custom informatics support for genome sequencing projects remains a major impediment to the accessibility of high-throughput sequence data.

Results

We present a self-contained, automated high-throughput open source genome sequencing and computational genomics pipeline suitable for prokaryotic sequencing projects. The pipeline has been used at the Georgia Institute of Techno

SUBMITTER: Kislyuk AO 

PROVIDER: S-EPMC2905547 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature