Relatedness of baculovirus and gypsy retrotransposon envelope proteins.

ABSTRACT:

Background

Current evidence suggests that lepidopteran baculoviruses may be divided into two phylogenetic groups based on their envelope fusion proteins. One group utilizes gp64, a low pH-dependent envelope fusion protein, whereas the other employs a protein family (e.g. LD130 in the Lymantria dispar nucleopolyhedrovirus) unrelated to gp64, but that is also low pH-dependent. Database searches with members of the LD130 protein family often record significant levels of homology to envelope proteins from a number of insect retrovirus-like transposable elements of the gypsy class. In this report, the significance of the homology between these two types of envelope proteins is analyzed.

Results

The significance of the alignment scores was evaluated using Z-scores that were calcul

SUBMITTER: Rohrmann GF 

PROVIDER: S-EPMC29073 | biostudies-literature | 2001

REPOSITORIES: biostudies-literature