Subsequent neoplasms in 5-year survivors of childhood cancer: the Childhood Cancer Survivor Study.

ABSTRACT:

Background

The occurrence of subsequent neoplasms has direct impact on the quantity and quality of life in cancer survivors. We have expanded our analysis of these events in the Childhood Cancer Survivor Study (CCSS) to better understand the occurrence of these events as the survivor population ages.

Methods

The incidence of and risk for subsequent neoplasms occurring 5 years or more after the childhood cancer diagnosis were determined among 14,359 5-year survivors in the CCSS who were treated from 1970 through 1986 and who were at a median age of 30 years (range = 5-56 years) for this analysis. At 30 years after childhood cancer diagnosis, we calculated cumulative incidence at 30 years of subsequent neoplasms and calculated standardized incidence ratios (SIRs), excess absol

SUBMITTER: Friedman DL 

PROVIDER: S-EPMC2907408 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature