Ontology highlight
ABSTRACT:
SUBMITTER: Castillo B
PROVIDER: S-EPMC2908921 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Castillo Betzaida B Delgado Yamixa Y Barletta Gabriel G Griebenow Kai K
Tetrahedron 20100301 12
Enzyme catalysis in organic solvents is a powerful tool for stereo-selective synthesis but the enantioselectivity is still hard to predict. To overcome this obstacle, we employed a nanoparticulate formulation of subtilisin Carlsberg (SC) and designed a series of 14 structurally related racemic alcohols. They were employed in the model transesterification reaction with vinyl butyrate and the enantioselectivities were determined. In general, short alcohol side chains led to low enantioselectivties ...[more]