Newer insights into the mechanism of action of Psidium guajava L. leaves in infectious diarrhoea.

ABSTRACT:

Background

Psidium guajava L., Myrtaceae, is used widely in traditional medicine for the treatment of diarrhoea, dysentery, gastroenteritis, stomachaches, and indigestion. However, the effect of the leaf extract of P. guajava on the pathogenesis of infectious diarrhoea has not been studied. The present study evaluates the effect of a hot aqueous extract (decoction) of dried leaves of P. guajava on parameters associated with pathogenicity of infectious diarrhoea. The aim was to understand its possible mechanism(s) of action in controlling infectious diarrhoea and compare it with quercetin, one of the most reported active constituents of P. guajava with antidiarrhoeal activity.

Methods

The crude decoction and quercetin were studied for their antibacterial activity and effect o

SUBMITTER: Birdi T 

PROVIDER: S-EPMC2911405 | biostudies-literature | 2010 Jun

REPOSITORIES: biostudies-literature