Pulse-pressure variation and hemodynamic response in patients with elevated pulmonary artery pressure: a clinical study.

ABSTRACT:

Introduction

Pulse-pressure variation (PPV) due to increased right ventricular afterload and dysfunction may misleadingly suggest volume responsiveness. We aimed to assess prediction of volume responsiveness with PPV in patients with increased pulmonary artery pressure.

Methods

Fifteen cardiac surgery patients with a history of increased pulmonary artery pressure (mean pressure, 27 +/- 5 mm Hg (mean +/- SD) before fluid challenges) and seven septic shock patients (mean pulmonary artery pressure, 33 +/- 10 mm Hg) were challenged with 200 ml hydroxyethyl starch boli ordered on clinical indication. PPV, right ventricular ejection fraction (EF) and end-diastolic volume (EDV), stroke volume (SV), and intravascular pressures were measured before and after volume challenges.

Res

SUBMITTER: Wyler von Ballmoos M 

PROVIDER: S-EPMC2911757 | biostudies-literature | 2010

REPOSITORIES: biostudies-literature