Medial temporal lobe activity during complex discrimination of faces, objects, and scenes: Effects of viewpoint.

ABSTRACT: The medial temporal lobe (MTL), a set of heavily interconnected structures including the hippocampus and underlying entorhinal, perirhinal and parahippocampal cortex, is traditionally believed to be part of a unitary system dedicated to declarative memory. Recent studies, however, demonstrated perceptual impairments in amnesic individuals with MTL damage, with hippocampal lesions causing scene discrimination deficits, and perirhinal lesions causing object and face discrimination deficits. The degree of impairment on these tasks was influenced by the need to process complex conjunctions of features: discriminations requiring the integration of multiple visual features caused deficits, whereas discriminations that could be solved on the basis of a single feature did not. Here, we address the

SUBMITTER: Barense MD 

PROVIDER: S-EPMC2912509 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature