Chemoreception regulates chemical access to mouse vomeronasal organ: role of solitary chemosensory cells.

ABSTRACT: Controlling stimulus access to sensory organs allows animals to optimize sensory reception and prevent damage. The vomeronasal organ (VNO) detects pheromones and other semiochemicals to regulate innate social and sexual behaviors. This semiochemical detection generally requires the VNO to draw in chemical fluids, such as bodily secretions, which are complex in composition and can be contaminated. Little is known about whether and how chemical constituents are monitored to regulate the fluid access to the VNO. Using transgenic mice and immunolabeling, we found that solitary chemosensory cells (SCCs) reside densely at the entrance duct of the VNO. In this region, most of the intraepithelial trigeminal fibers innervate the SCCs, indicating that SCCs relay sensory information onto the trigemin

SUBMITTER: Ogura T 

PROVIDER: S-EPMC2912856 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature