Sparse coding and high-order correlations in fine-scale cortical networks.

ABSTRACT: Connectivity in the cortex is organized at multiple scales, suggesting that scale-dependent correlated activity is particularly important for understanding the behaviour of sensory cortices and their function in stimulus encoding. We analysed the scale-dependent structure of cortical interactions by using maximum entropy models to characterize multiple-tetrode recordings from primary visual cortex of anaesthetized macaque monkeys (Macaca mulatta). We compared the properties of firing patterns among local clusters of neurons (<300 microm apart) with those of neurons separated by larger distances (600-2,500 microm). Here we report that local firing patterns are distinctive: whereas multi-neuronal firing patterns at larger distances can be predicted by pairwise interactions, patterns within l

SUBMITTER: Ohiorhenuan IE 

PROVIDER: S-EPMC2912961 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature