Association analyses of vitamin D-binding protein gene with compression strength index variation in Caucasian nuclear families.

ABSTRACT:

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This study was conducted to test whether there exists an association between vitamin D-binding protein (DBP) gene and compression strength index (CSI) phenotype. Candidate gene association analyses were conducted in total sample, male subgroup, and female subgroup, respectively. Two single-nucleotide polymorphisms (SNPs) with significant association results were found in males, suggesting the importance of DBP gene polymorphisms on the variation in CSI especially in Caucasian males.

Introduction

CSI of the femoral neck (FN) is a newly developed phenotype integrating information about bone size, body size, and bone mineral density. It is considered to have the potential to improve the performance of risk assessment for hip fractures because it is based on a combina

SUBMITTER: Xu XH 

PROVIDER: S-EPMC2914268 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature