Motor preparatory activity in posterior parietal cortex is modulated by subjective absolute value.

ABSTRACT: For optimal response selection, the consequences associated with behavioral success or failure must be appraised. To determine how monetary consequences influence the neural representations of motor preparation, human brain activity was scanned with fMRI while subjects performed a complex spatial visuomotor task. At the beginning of each trial, reward context cues indicated the potential gain and loss imposed for correct or incorrect trial completion. FMRI-activity in canonical reward structures reflected the expected value related to the context. In contrast, motor preparatory activity in posterior parietal and premotor cortex peaked in high "absolute value" (high gain or loss) conditions: being highest for large gains in subjects who believed they performed well while being highest for l

SUBMITTER: Iyer A 

PROVIDER: S-EPMC2914636 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature