Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial.

ABSTRACT:

Context

Guidelines recommend that exercise training be considered for medically stable outpatients with heart failure. Previous studies have not had adequate statistical power to measure the effects of exercise training on clinical outcomes.

Objective

To test the efficacy and safety of exercise training among patients with heart failure.

Design, setting, and patients

Multicenter, randomized controlled trial of 2331 medically stable outpatients with heart failure and reduced ejection fraction. Participants in Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) were randomized from April 2003 through February 2007 at 82 centers within the United States, Canada, and France; median follow-up was 30 months.

Interventions

Usual c

SUBMITTER: O'Connor CM 

PROVIDER: S-EPMC2916661 | biostudies-literature | 2009 Apr

REPOSITORIES: biostudies-literature