Ethnic differences in lipoprotein subclasses in obese adolescents: importance of liver and intraabdominal fat accretion.

ABSTRACT:

Background

Recently, the deleterious metabolic effects of visceral fat [visceral adipose tissue (VAT)] deposition were challenged, and liver fat emerged as having a key independent role in the modulation of cardiometabolic risk factors.

Objective

We explored the relation between liver fat content and VAT in 3 ethnic groups and evaluated whether the ethnic differences in the distributions of lipoprotein concentrations and sizes were associated with the hepatic fat fraction (HFF), VAT, or both.

Design

In a multiethnic group of 33 white, 33 African American, and 33 Hispanic obese adolescents with normal glucose tolerance, we measured VAT and HFF by using magnetic resonance imaging. Fasting lipoprotein particle number and size were measured by using nuclear magnetic reson

SUBMITTER: D'Adamo E 

PROVIDER: S-EPMC2921534 | biostudies-literature | 2010 Sep

REPOSITORIES: biostudies-literature