Conjugate addition of lithiated methyl pyridines to enones.

ABSTRACT: Preparatively useful conjugate addition of lithiated methyl pyridines to cyclic and acyclic enones is reported. Addition of 2-picoline to 3-penten-2-one led to a concise synthesis of the alkaloids (+/-)-senepodine G and (+/-)-cermizine C.

SUBMITTER: Taber DF 

PROVIDER: S-EPMC2921646 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature