Ontology highlight
ABSTRACT:
SUBMITTER: Oblak AL
PROVIDER: S-EPMC2923229 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Oblak Adrian L AL Gibbs Terrell T TT Blatt Gene J GJ
Journal of neurochemistry 20100612 5
Autism is a behaviorally defined neurodevelopmental disorder and among its symptoms are disturbances in face and emotional processing. Emerging evidence demonstrates abnormalities in the GABAergic (gamma-aminobutyric acid) system in autism, which likely contributes to these deficits. GABA(B) receptors play an important role in modulating synapses and maintaining the balance of excitation-inhibition in the brain. The density of GABA(B) receptors in subjects with autism and matched controls was qu ...[more]